Altheome
Assay Development & ScreeningProtein Sciences & ReagentsPK/PD & ModelingOncologyHematologySmall MoleculePeptide
Quick answer
Outsourcing a CNS or neurology program means sourcing CRO and CDMO partners who understand the blood-brain barrier, validated disease models (Alzheimer's, Parkinson's, epilepsy, ALS, MS, pain), CSF and PET biomarkers, behavioral and electrophysiology readouts, and CNS-experienced clinical sites and raters. On BioBridgeX, buyers compare qualified suppliers as the neutral marketplace, free for buyers, in one place.
CNS / Neurology CRO and CDMO vendors (141)
UNIQ Trials
PK/PD & ModelingBioanalytical ServicesIND / Regulatory Package AuthoringOncologyHematologySmall MoleculePeptide
Apeloa Pharmaceutical
Target ID & ValidationAssay Development & ScreeningHit IdentificationOncologyHematologySmall MoleculePeptide
TRiCBIO
Target ID & ValidationAssay Development & ScreeningHit IdentificationOncologyCNS / NeurologySmall MoleculePeptide
VCHP Clinical Solutions
Computational / AI-Driven DiscoveryPK/PD & ModelingPhase 1 / Early Clinical UnitOncologyHematologySmall MoleculePeptide
AAPharmaSyn
Hit IdentificationHit-to-LeadLead OptimizationOncologyHematologySmall MoleculeRadiopharmaceutical / Radioligand
Famar Group
Unclaimed · public records
CDMO · Formulation Development, LNP / Delivery Formulation, Process Development
Formulation DevelopmentLNP / Delivery FormulationProcess DevelopmentMetabolic / EndocrinologyCardiovascularSmall MoleculeProtein / Enzyme (Recombinant)
AbbVie Contract Manufacturing
Unclaimed · public records
CRO & CDMO · Drug Substance: Small Molecule / API, Drug Substance: Biologics, Formulation Development
Drug Substance: Small Molecule / APIDrug Substance: BiologicsFormulation DevelopmentOncologyImmunology & InflammationSmall MoleculeMonoclonal Antibody (mAb)
Novocol Pharma
Unclaimed · public records
CDMO · Formulation Development, LNP / Delivery Formulation, Process Development
Formulation DevelopmentLNP / Delivery FormulationProcess DevelopmentMetabolic / EndocrinologyCNS / NeurologySmall MoleculeProtein / Enzyme (Recombinant)
Kindeva Drug Delivery
Unclaimed · public records
CDMO · Formulation Development, LNP / Delivery Formulation, Process Development
Formulation DevelopmentLNP / Delivery FormulationProcess DevelopmentRespiratoryOncologySmall MoleculeProtein / Enzyme (Recombinant)
Curia Global
Unclaimed · public records
CRO & CDMO · Drug Substance: Small Molecule / API, Drug Substance: Biologics, Formulation Development
Drug Substance: Small Molecule / APIDrug Substance: BiologicsFormulation DevelopmentOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
Siegfried Holding
Unclaimed · public records
CRO & CDMO · Drug Substance: Small Molecule / API, Formulation Development, LNP / Delivery Formulation
Drug Substance: Small Molecule / APIFormulation DevelopmentLNP / Delivery FormulationOncologyCNS / NeurologySmall MoleculeProtein / Enzyme (Recombinant)
Aenova Group
Unclaimed · public records
CDMO · Formulation Development, LNP / Delivery Formulation, Process Development
Formulation DevelopmentLNP / Delivery FormulationProcess DevelopmentOncologyImmunology & InflammationSmall MoleculeProtein / Enzyme (Recombinant)
Vetter Pharma
Unclaimed · public records
CDMO · Formulation Development, LNP / Delivery Formulation, Process Development
Formulation DevelopmentLNP / Delivery FormulationProcess DevelopmentOncologyImmunology & InflammationMonoclonal Antibody (mAb)Protein / Enzyme (Recombinant)
Recipharm
Unclaimed · public records
CDMO · mRNA / RNA Manufacturing, LNP / Delivery Formulation, Drug Product Manufacturing
mRNA / RNA ManufacturingLNP / Delivery FormulationDrug Product ManufacturingInfectious DiseaseOncologymRNA / saRNASmall Molecule
Phosphorex
Unclaimed · public records
CDMO · LNP / Delivery Formulation, Formulation Development, Process Development
LNP / Delivery FormulationFormulation DevelopmentProcess DevelopmentOncologyRare / Orphan DiseasemRNA / saRNAOligonucleotide (ASO / siRNA)
Ascendia Pharmaceutical Solutions
Unclaimed · public records
CDMO · LNP / Delivery Formulation, Formulation Development, Drug Product Manufacturing
LNP / Delivery FormulationFormulation DevelopmentDrug Product ManufacturingOncologyCNS / NeurologymRNA / saRNASmall Molecule
Agilent Technologies
Unclaimed · public records
CDMO · Peptide / Oligo Synthesis, Process Development, Analytical Development
Peptide / Oligo SynthesisProcess DevelopmentAnalytical DevelopmentRare / Orphan DiseaseOncologyOligonucleotide (ASO / siRNA)
Nitto Avecia Pharma Services
Unclaimed · public records
CDMO · Peptide / Oligo Synthesis, Process Development, Analytical Development
Peptide / Oligo SynthesisProcess DevelopmentAnalytical DevelopmentRare / Orphan DiseaseOncologyOligonucleotide (ASO / siRNA)
Ascend Advanced Therapies
Unclaimed · public records
CDMO · Viral Vector Manufacturing, Process Development, Analytical Development
Viral Vector ManufacturingProcess DevelopmentAnalytical DevelopmentRare / Orphan DiseaseCNS / NeurologyGene Therapy (AAV / Viral Vector)
PackGene Biotech
Unclaimed · public records
CRO & CDMO · Viral Vector Manufacturing, Plasmid DNA Manufacturing, mRNA / RNA Manufacturing
Viral Vector ManufacturingPlasmid DNA ManufacturingmRNA / RNA ManufacturingOncologyRare / Orphan DiseaseGene Therapy (AAV / Viral Vector)mRNA / saRNA
Viralgen (AskBio)
Unclaimed · public records
CDMO · Viral Vector Manufacturing, Process Development, Analytical Development
Viral Vector ManufacturingProcess DevelopmentAnalytical DevelopmentRare / Orphan DiseaseCNS / NeurologyGene Therapy (AAV / Viral Vector)
Andelyn Biosciences
Unclaimed · public records
CDMO · Viral Vector Manufacturing, Plasmid DNA Manufacturing, Process Development
Viral Vector ManufacturingPlasmid DNA ManufacturingProcess DevelopmentRare / Orphan DiseaseCNS / NeurologyGene Therapy (AAV / Viral Vector)Plasmid DNA
Forge Biologics (Ajinomoto)
Unclaimed · public records
CDMO · Viral Vector Manufacturing, Plasmid DNA Manufacturing, Process Development
Viral Vector ManufacturingPlasmid DNA ManufacturingProcess DevelopmentRare / Orphan DiseaseCNS / NeurologyGene Therapy (AAV / Viral Vector)Plasmid DNA
Oxford Biomedica
Unclaimed · public records
CDMO · Viral Vector Manufacturing, Plasmid DNA Manufacturing, Process Development
Viral Vector ManufacturingPlasmid DNA ManufacturingProcess DevelopmentOncologyHematologyGene Therapy (AAV / Viral Vector)Cell Therapy (CAR-T / NK / TIL)
Catalent
Unclaimed · public records
CDMO · Viral Vector Manufacturing, Cell Therapy Manufacturing, Plasmid DNA Manufacturing
Viral Vector ManufacturingCell Therapy ManufacturingPlasmid DNA ManufacturingOncologyHematologyGene Therapy (AAV / Viral Vector)Cell Therapy (CAR-T / NK / TIL)
Polpharma Biologics
Unclaimed · public records
CDMO · Cell Line / Strain Development, Process Development, Analytical Development
Cell Line / Strain DevelopmentProcess DevelopmentAnalytical DevelopmentImmunology & InflammationOncologyMonoclonal Antibody (mAb)Protein / Enzyme (Recombinant)
Boehringer Ingelheim BioXcellence
Unclaimed · public records
CDMO · Cell Line / Strain Development, Process Development, Analytical Development
Cell Line / Strain DevelopmentProcess DevelopmentAnalytical DevelopmentOncologyImmunology & InflammationMonoclonal Antibody (mAb)Bispecific / Multispecific Antibody
Teva API (TAPI)
Unclaimed · public records
CDMO · Drug Substance: Small Molecule / API, Process Development, Analytical Development
Drug Substance: Small Molecule / APIProcess DevelopmentAnalytical DevelopmentOncologyCNS / NeurologySmall MoleculePeptide
Almac Group
Unclaimed · public records
CRO & CDMO · Medicinal & Synthetic Chemistry, Process Development, Drug Substance: Small Molecule / API
Medicinal & Synthetic ChemistryProcess DevelopmentDrug Substance: Small Molecule / APIOncologyCNS / NeurologySmall Molecule
Onyx Scientific (IPCA)
Unclaimed · public records
CDMO · Medicinal & Synthetic Chemistry, Process Development, Drug Substance: Small Molecule / API
Medicinal & Synthetic ChemistryProcess DevelopmentDrug Substance: Small Molecule / APIOncologyCNS / NeurologySmall Molecule
Laurus Labs (Laurus Synthesis)
Unclaimed · public records
CDMO · Medicinal & Synthetic Chemistry, Process Development, Drug Substance: Small Molecule / API
Medicinal & Synthetic ChemistryProcess DevelopmentDrug Substance: Small Molecule / APIInfectious DiseaseOncologySmall Molecule
Navin Molecular (Navin Fluorine)
Unclaimed · public records
CDMO · Medicinal & Synthetic Chemistry, Process Development, Drug Substance: Small Molecule / API
Medicinal & Synthetic ChemistryProcess DevelopmentDrug Substance: Small Molecule / APIOncologyCNS / NeurologySmall Molecule
F.I.S. (Fabbrica Italiana Sintetici)
Unclaimed · public records
CDMO · Medicinal & Synthetic Chemistry, Process Development, Drug Substance: Small Molecule / API
Medicinal & Synthetic ChemistryProcess DevelopmentDrug Substance: Small Molecule / APIOncologyCNS / NeurologySmall Molecule
PROCOS
Unclaimed · public records
CDMO · Medicinal & Synthetic Chemistry, Process Development, Drug Substance: Small Molecule / API
Medicinal & Synthetic ChemistryProcess DevelopmentDrug Substance: Small Molecule / APIOncologyCardiovascularSmall MoleculeAntibody-Drug Conjugate (ADC)
Sumitomo Chemical (Pharmaceuticals/CDMO)
Unclaimed · public records
CDMO · Process Development, Drug Substance: Small Molecule / API, Analytical Development
Process DevelopmentDrug Substance: Small Molecule / APIAnalytical DevelopmentOncologyCNS / NeurologySmall Molecule
Fermion (Orion Corporation)
Unclaimed · public records
CDMO · Process Development, Drug Substance: Small Molecule / API, Analytical Development
Process DevelopmentDrug Substance: Small Molecule / APIAnalytical DevelopmentOncologyCNS / NeurologySmall Molecule
Minakem (Minafin Group)
Unclaimed · public records
CDMO · Medicinal & Synthetic Chemistry, Process Development, Drug Substance: Small Molecule / API
Medicinal & Synthetic ChemistryProcess DevelopmentDrug Substance: Small Molecule / APIOncologyCNS / NeurologySmall Molecule
Curia (formerly AMRI)
Unclaimed · public records
CRO & CDMO · Target ID & Validation, Hit-to-Lead, Lead Optimization
Target ID & ValidationHit-to-LeadLead OptimizationOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
Bachem
Unclaimed · public records
CDMO · Peptide / Oligo Synthesis, Process Development, Analytical Development
Peptide / Oligo SynthesisProcess DevelopmentAnalytical DevelopmentMetabolic / EndocrinologyOncologyPeptideOligonucleotide (ASO / siRNA)
AMPAC Fine Chemicals (SK pharmteco)
Unclaimed · public records
CDMO · Medicinal & Synthetic Chemistry, Process Development, Drug Substance: Small Molecule / API
Medicinal & Synthetic ChemistryProcess DevelopmentDrug Substance: Small Molecule / APIOncologyCNS / NeurologySmall MoleculeOligonucleotide (ASO / siRNA)
Veranova
Unclaimed · public records
CDMO · Medicinal & Synthetic Chemistry, Process Development, Drug Substance: Small Molecule / API
Medicinal & Synthetic ChemistryProcess DevelopmentDrug Substance: Small Molecule / APIOncologyCNS / NeurologySmall MoleculePeptide
Pfizer CentreOne
Unclaimed · public records
CRO & CDMO · Drug Substance: Small Molecule / API, Process Development, Analytical Development
Drug Substance: Small Molecule / APIProcess DevelopmentAnalytical DevelopmentInfectious DiseaseOncologySmall MoleculeMonoclonal Antibody (mAb)
Noramco
Unclaimed · public records
CDMO · Drug Substance: Small Molecule / API, Process Development, Analytical Development
Drug Substance: Small Molecule / APIProcess DevelopmentAnalytical DevelopmentCNS / NeurologyOncologySmall Molecule
Thermo Fisher Scientific (Patheon)
Unclaimed · public records
CRO & CDMO · Process Development, Drug Substance: Small Molecule / API, Analytical Development
Process DevelopmentDrug Substance: Small Molecule / APIAnalytical DevelopmentOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
Divi's Laboratories
Unclaimed · public records
CDMO · Medicinal & Synthetic Chemistry, Process Development, Drug Substance: Small Molecule / API
Medicinal & Synthetic ChemistryProcess DevelopmentDrug Substance: Small Molecule / APIOncologyCardiovascularSmall MoleculePeptide
Dr. Reddy's Custom Pharma Services (CPS)
Unclaimed · public records
CRO & CDMO · Process Development, Drug Substance: Small Molecule / API, Analytical Development
Process DevelopmentDrug Substance: Small Molecule / APIAnalytical DevelopmentOncologyCardiovascularSmall MoleculePeptide
Piramal Pharma Solutions
Unclaimed · public records
CRO & CDMO · Hit-to-Lead, Lead Optimization, Medicinal & Synthetic Chemistry
Hit-to-LeadLead OptimizationMedicinal & Synthetic ChemistryOncologyCNS / NeurologySmall MoleculeAntibody-Drug Conjugate (ADC)
EUROAPI
Unclaimed · public records
CDMO · Drug Substance: Small Molecule / API, Process Development, Analytical Development
Drug Substance: Small Molecule / APIProcess DevelopmentAnalytical DevelopmentOncologyCardiovascularSmall MoleculePeptide
Seqens
Unclaimed · public records
CDMO · Medicinal & Synthetic Chemistry, Process Development, Drug Substance: Small Molecule / API
Medicinal & Synthetic ChemistryProcess DevelopmentDrug Substance: Small Molecule / APIOncologyCNS / NeurologySmall MoleculeAntibody-Drug Conjugate (ADC)
Olon Group
Unclaimed · public records
CDMO · Drug Substance: Small Molecule / API, Process Development, Analytical Development
Drug Substance: Small Molecule / APIProcess DevelopmentAnalytical DevelopmentOncologyInfectious DiseaseSmall MoleculePeptide
DOTTIKON ES
Unclaimed · public records
CDMO · Medicinal & Synthetic Chemistry, Process Development, Drug Substance: Small Molecule / API
Medicinal & Synthetic ChemistryProcess DevelopmentDrug Substance: Small Molecule / APIOncologyCNS / NeurologySmall Molecule
Hovione
Unclaimed · public records
CDMO · Drug Substance: Small Molecule / API, Process Development, Analytical Development
Drug Substance: Small Molecule / APIProcess DevelopmentAnalytical DevelopmentOncologyRespiratorySmall Molecule
CordenPharma
Unclaimed · public records
CRO & CDMO · Drug Substance: Small Molecule / API, Process Development, Analytical Development
Drug Substance: Small Molecule / APIProcess DevelopmentAnalytical DevelopmentOncologyMetabolic / EndocrinologySmall MoleculePeptide
Sterling Pharma Solutions
Unclaimed · public records
CDMO · Medicinal & Synthetic Chemistry, Process Development, Drug Substance: Small Molecule / API
Medicinal & Synthetic ChemistryProcess DevelopmentDrug Substance: Small Molecule / APIOncologyCNS / NeurologySmall MoleculeAntibody-Drug Conjugate (ADC)
WuXi STA (WuXi AppTec)
Unclaimed · public records
CRO & CDMO · Medicinal & Synthetic Chemistry, Process Development, Analytical Development
Medicinal & Synthetic ChemistryProcess DevelopmentAnalytical DevelopmentOncologyHematologySmall MoleculePeptide
Asymchem
Unclaimed · public records
CRO & CDMO · Medicinal & Synthetic Chemistry, Process Development, Drug Substance: Small Molecule / API
Medicinal & Synthetic ChemistryProcess DevelopmentDrug Substance: Small Molecule / APIOncologyMetabolic / EndocrinologySmall MoleculePeptide
Siegfried
Unclaimed · public records
CDMO · Drug Substance: Small Molecule / API, Process Development, Analytical Development
Drug Substance: Small Molecule / APIProcess DevelopmentAnalytical DevelopmentOncologyCNS / NeurologySmall Molecule
Cambrex
Unclaimed · public records
CDMO · Drug Substance: Small Molecule / API, Process Development, Analytical Development
Drug Substance: Small Molecule / APIProcess DevelopmentAnalytical DevelopmentOncologyRare / Orphan DiseaseSmall MoleculeAntibody-Drug Conjugate (ADC)
Lonza
Unclaimed · public records
CRO & CDMO · Drug Substance: Small Molecule / API, Process Development, Analytical Development
Drug Substance: Small Molecule / APIProcess DevelopmentAnalytical DevelopmentOncologyRare / Orphan DiseaseSmall MoleculeAntibody-Drug Conjugate (ADC)
Eurofins (Pharma Discovery & Bioanalytical Services)
Unclaimed · public records
CRO & CDMO · Bioanalytical Services, Central Laboratory Services, Genetic Toxicology
Bioanalytical ServicesCentral Laboratory ServicesGenetic ToxicologyOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
QPS Holdings
Unclaimed · public records
CRO · Bioanalytical Services, DMPK / ADME, GLP Toxicology
Bioanalytical ServicesDMPK / ADMEGLP ToxicologyCNS / NeurologyOncologySmall MoleculeMonoclonal Antibody (mAb)
Simulations Plus
Unclaimed · public records
CRO · PK/PD & Modeling, DMPK / ADME, In Vitro / Early Toxicology
PK/PD & ModelingDMPK / ADMEIn Vitro / Early ToxicologyOncologyCNS / NeurologySmall MoleculePeptide
Certara
Unclaimed · public records
CRO · PK/PD & Modeling, Biostatistics & Statistical Programming, Medical Writing
PK/PD & ModelingBiostatistics & Statistical ProgrammingMedical WritingOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
Labcorp
Unclaimed · public records
CRO & CDMO · Central Laboratory Services, GLP Toxicology, Safety Pharmacology
Central Laboratory ServicesGLP ToxicologySafety PharmacologyOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
Pharmacology Discovery Services (PDS)
Unclaimed · public records
CRO · In Vitro Pharmacology, Safety Pharmacology, Assay Development & Screening
In Vitro PharmacologySafety PharmacologyAssay Development & ScreeningCNS / NeurologyMetabolic / EndocrinologySmall MoleculePeptide
InnoSer Laboratories
Unclaimed · public records
CRO · In Vitro Pharmacology, Biomarker Discovery & Development, PK/PD & Modeling
In Vitro PharmacologyBiomarker Discovery & DevelopmentPK/PD & ModelingOncologyHematologySmall MoleculeMonoclonal Antibody (mAb)
Hooke Laboratories
Unclaimed · public records
CRO · In Vitro Pharmacology, Biomarker Discovery & Development
In Vitro PharmacologyBiomarker Discovery & DevelopmentImmunology & InflammationCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
GemPharmatech
Unclaimed · public records
CRO · In Vitro Pharmacology, Target ID & Validation, Biomarker Discovery & Development
In Vitro PharmacologyTarget ID & ValidationBiomarker Discovery & DevelopmentOncologyMetabolic / EndocrinologySmall MoleculeMonoclonal Antibody (mAb)
Labcorp (Labcorp Drug Development)
Unclaimed · public records
CRO · In Vitro Pharmacology, DMPK / ADME, GLP Toxicology
In Vitro PharmacologyDMPK / ADMEGLP ToxicologyOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
WuXi AppTec (WuXi Biology)
Unclaimed · public records
CRO & CDMO · In Vitro Pharmacology, DMPK / ADME, Bioanalytical Services
In Vitro PharmacologyDMPK / ADMEBioanalytical ServicesOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
The Jackson Laboratory (JAX)
Unclaimed · public records
CRO · In Vitro Pharmacology, Biomarker Discovery & Development, Target ID & Validation
In Vitro PharmacologyBiomarker Discovery & DevelopmentTarget ID & ValidationOncologyHematologySmall MoleculeMonoclonal Antibody (mAb)
BenevolentAI
Unclaimed · public records
CRO · Target ID & Validation, Computational / AI-Driven Discovery
Target ID & ValidationComputational / AI-Driven DiscoveryImmunology & InflammationCNS / NeurologySmall Molecule
Iktos
Unclaimed · public records
CRO · Hit-to-Lead, Lead Optimization, Medicinal & Synthetic Chemistry
Hit-to-LeadLead OptimizationMedicinal & Synthetic ChemistryOncologyCNS / NeurologySmall MoleculePROTAC / Targeted Protein Degrader
Atomwise
Unclaimed · public records
CRO · Target ID & Validation, Hit-to-Lead, Computational / AI-Driven Discovery
Target ID & ValidationHit-to-LeadComputational / AI-Driven DiscoveryOncologyInfectious DiseaseSmall Molecule
Insilico Medicine
Unclaimed · public records
CRO · Target ID & Validation, Hit-to-Lead, Lead Optimization
Target ID & ValidationHit-to-LeadLead OptimizationOncologyRespiratorySmall Molecule
Recursion Pharmaceuticals
Unclaimed · public records
CRO · Target ID & Validation, Assay Development & Screening, Hit-to-Lead
Target ID & ValidationAssay Development & ScreeningHit-to-LeadOncologyRare / Orphan DiseaseSmall Molecule
OpenEye, Cadence Molecular Sciences
Unclaimed · public records
CRO · Hit-to-Lead, Lead Optimization, Computational / AI-Driven Discovery
Hit-to-LeadLead OptimizationComputational / AI-Driven DiscoveryOncologyCNS / NeurologySmall MoleculePROTAC / Targeted Protein Degrader
Cresset
Unclaimed · public records
CRO · Hit-to-Lead, Lead Optimization, Medicinal & Synthetic Chemistry
Hit-to-LeadLead OptimizationMedicinal & Synthetic ChemistryOncologyCNS / NeurologySmall MoleculePROTAC / Targeted Protein Degrader
Schrodinger
Unclaimed · public records
CRO · Target ID & Validation, Hit-to-Lead, Lead Optimization
Target ID & ValidationHit-to-LeadLead OptimizationOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
Hypha Discovery
Unclaimed · public records
CRO · Medicinal & Synthetic Chemistry, DMPK / ADME, Bioanalytical Services
Medicinal & Synthetic ChemistryDMPK / ADMEBioanalytical ServicesOncologyCNS / NeurologySmall Molecule
ChemDiv
Unclaimed · public records
CRO · Assay Development & Screening, Hit-to-Lead, Lead Optimization
Assay Development & ScreeningHit-to-LeadLead OptimizationOncologyCNS / NeurologySmall MoleculePROTAC / Targeted Protein Degrader
Enamine
Unclaimed · public records
CRO · Assay Development & Screening, Hit-to-Lead, Lead Optimization
Assay Development & ScreeningHit-to-LeadLead OptimizationOncologyCNS / NeurologySmall MoleculePROTAC / Targeted Protein Degrader
Proteros Biostructures
Unclaimed · public records
CRO · Assay Development & Screening, Hit-to-Lead, Structural Biology
Assay Development & ScreeningHit-to-LeadStructural BiologyOncologyImmunology & InflammationSmall MoleculePROTAC / Targeted Protein Degrader
HitGen
Unclaimed · public records
CRO · Assay Development & Screening, Hit-to-Lead, Lead Optimization
Assay Development & ScreeningHit-to-LeadLead OptimizationOncologyImmunology & InflammationSmall MoleculePROTAC / Targeted Protein Degrader
X-Chem
Unclaimed · public records
CRO · Assay Development & Screening, Hit-to-Lead, Lead Optimization
Assay Development & ScreeningHit-to-LeadLead OptimizationOncologyImmunology & InflammationSmall MoleculePROTAC / Targeted Protein Degrader
Curia
Unclaimed · public records
CRO & CDMO · Target ID & Validation, Assay Development & Screening, Hit-to-Lead
Target ID & ValidationAssay Development & ScreeningHit-to-LeadOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
BioDuro
Unclaimed · public records
CRO & CDMO · Target ID & Validation, Assay Development & Screening, Hit-to-Lead
Target ID & ValidationAssay Development & ScreeningHit-to-LeadOncologyCNS / NeurologySmall MoleculePeptide
Selvita
Unclaimed · public records
CRO · Target ID & Validation, Assay Development & Screening, Hit-to-Lead
Target ID & ValidationAssay Development & ScreeningHit-to-LeadOncologyCNS / NeurologySmall MoleculePROTAC / Targeted Protein Degrader
Charnwood Discovery
Unclaimed · public records
CRO · Target ID & Validation, Assay Development & Screening, Hit-to-Lead
Target ID & ValidationAssay Development & ScreeningHit-to-LeadOncologyCNS / NeurologySmall MoleculePROTAC / Targeted Protein Degrader
Domainex
Unclaimed · public records
CRO · Target ID & Validation, Assay Development & Screening, Hit-to-Lead
Target ID & ValidationAssay Development & ScreeningHit-to-LeadOncologyImmunology & InflammationSmall MoleculePROTAC / Targeted Protein Degrader
Sygnature Discovery
Unclaimed · public records
CRO · Target ID & Validation, Assay Development & Screening, Hit-to-Lead
Target ID & ValidationAssay Development & ScreeningHit-to-LeadOncologyCNS / NeurologySmall MoleculePeptide
Syngene International
Unclaimed · public records
CRO & CDMO · GLP Toxicology, Safety Pharmacology, DMPK / ADME
GLP ToxicologySafety PharmacologyDMPK / ADMEOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
Aragen Life Sciences
Unclaimed · public records
CRO & CDMO · DMPK / ADME, GLP Toxicology, Safety Pharmacology
DMPK / ADMEGLP ToxicologySafety PharmacologyOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
Sai Life Sciences
Unclaimed · public records
CRO & CDMO · DMPK / ADME, In Vitro / Early Toxicology, GLP Toxicology
DMPK / ADMEIn Vitro / Early ToxicologyGLP ToxicologyOncologyCNS / NeurologySmall MoleculePeptide
JOINN Laboratories / Biomere
Unclaimed · public records
CRO · GLP Toxicology, Safety Pharmacology, Toxicokinetics (TK)
GLP ToxicologySafety PharmacologyToxicokinetics (TK)OncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
Lovelace Biomedical
Unclaimed · public records
CRO · GLP Toxicology, Safety Pharmacology, Toxicokinetics (TK)
GLP ToxicologySafety PharmacologyToxicokinetics (TK)RespiratoryInfectious DiseaseSmall MoleculeMonoclonal Antibody (mAb)
Vivotecnia
Unclaimed · public records
CRO · GLP Toxicology, Safety Pharmacology, Genetic Toxicology
GLP ToxicologySafety PharmacologyGenetic ToxicologyOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
Nuvisan
Unclaimed · public records
CRO & CDMO · DMPK / ADME, Bioanalytical Services, In Vitro / Early Toxicology
DMPK / ADMEBioanalytical ServicesIn Vitro / Early ToxicologyOncologyCNS / NeurologySmall MoleculePeptide
Oncodesign Services
Unclaimed · public records
CRO · In Vitro Pharmacology, DMPK / ADME, Bioanalytical Services
In Vitro PharmacologyDMPK / ADMEBioanalytical ServicesOncologyImmunology & InflammationSmall MoleculeMonoclonal Antibody (mAb)
Biotrial
Unclaimed · public records
CRO · Safety Pharmacology, GLP Toxicology, Toxicokinetics (TK)
Safety PharmacologyGLP ToxicologyToxicokinetics (TK)CardiovascularCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
Scantox
Unclaimed · public records
CRO · GLP Toxicology, Safety Pharmacology, Genetic Toxicology
GLP ToxicologySafety PharmacologyGenetic ToxicologyOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
Cyprotex (an Evotec company)
Unclaimed · public records
CRO · In Vitro / Early Toxicology, DMPK / ADME, Genetic Toxicology
In Vitro / Early ToxicologyDMPK / ADMEGenetic ToxicologyOncologyCNS / NeurologySmall MoleculePeptide
Evotec
Unclaimed · public records
CRO & CDMO · In Vitro / Early Toxicology, DMPK / ADME, Safety Pharmacology
In Vitro / Early ToxicologyDMPK / ADMESafety PharmacologyOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
Reaction Biology
Unclaimed · public records
CRO · Assay Development & Screening, In Vitro Pharmacology, Target ID & Validation
Assay Development & ScreeningIn Vitro PharmacologyTarget ID & ValidationOncologyImmunology & InflammationSmall MoleculePROTAC / Targeted Protein Degrader
Frontage Laboratories
Unclaimed · public records
CRO & CDMO · GLP Toxicology, Safety Pharmacology, Toxicokinetics (TK)
GLP ToxicologySafety PharmacologyToxicokinetics (TK)OncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
Eurofins Discovery
Unclaimed · public records
CRO · In Vitro / Early Toxicology, Safety Pharmacology, DMPK / ADME
In Vitro / Early ToxicologySafety PharmacologyDMPK / ADMEOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
WuXi AppTec
Unclaimed · public records
CRO & CDMO · GLP Toxicology, Safety Pharmacology, Genetic Toxicology
GLP ToxicologySafety PharmacologyGenetic ToxicologyOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
Inotiv
Unclaimed · public records
CRO · GLP Toxicology, Safety Pharmacology, Genetic Toxicology
GLP ToxicologySafety PharmacologyGenetic ToxicologyOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
Labcorp (Labcorp Drug Development / former Covance)
Unclaimed · public records
CRO & CDMO · GLP Toxicology, Safety Pharmacology, Genetic Toxicology
GLP ToxicologySafety PharmacologyGenetic ToxicologyOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
Charles River Laboratories
Unclaimed · public records
CRO & CDMO · GLP Toxicology, Safety Pharmacology, Genetic Toxicology
GLP ToxicologySafety PharmacologyGenetic ToxicologyOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
Avance Clinical
Unclaimed · public records
CRO · Clinical Operations, Phase 1 / Early Clinical Unit, Clinical Data Management
Clinical OperationsPhase 1 / Early Clinical UnitClinical Data ManagementOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
Cromos Pharma
Unclaimed · public records
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
Clinical OperationsClinical Data ManagementBiostatistics & Statistical ProgrammingOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
George Clinical (Emerald Clinical)
Unclaimed · public records
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
Clinical OperationsClinical Data ManagementBiostatistics & Statistical ProgrammingOncologyCardiovascularSmall MoleculeMonoclonal Antibody (mAb)
TFS HealthScience
Unclaimed · public records
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
Clinical OperationsClinical Data ManagementBiostatistics & Statistical ProgrammingOncologyHematologySmall MoleculeMonoclonal Antibody (mAb)
Cytel
Unclaimed · public records
CRO · Biostatistics & Statistical Programming, Clinical Data Management, Clinical Operations
Biostatistics & Statistical ProgrammingClinical Data ManagementClinical OperationsOncologyHematologySmall MoleculeMonoclonal Antibody (mAb)
Precision for Medicine
Unclaimed · public records
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
Clinical OperationsClinical Data ManagementBiostatistics & Statistical ProgrammingOncologyHematologySmall MoleculeMonoclonal Antibody (mAb)
Pharmaron
Unclaimed · public records
CRO & CDMO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
Clinical OperationsClinical Data ManagementBiostatistics & Statistical ProgrammingOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
WuXi Clinical
Unclaimed · public records
CRO · Clinical Operations, Phase 1 / Early Clinical Unit, Clinical Data Management
Clinical OperationsPhase 1 / Early Clinical UnitClinical Data ManagementOncologyHematologySmall MoleculeMonoclonal Antibody (mAb)
Tigermed
Unclaimed · public records
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
Clinical OperationsClinical Data ManagementBiostatistics & Statistical ProgrammingOncologyHematologySmall MoleculeMonoclonal Antibody (mAb)
CMIC Group
Unclaimed · public records
CRO & CDMO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
Clinical OperationsClinical Data ManagementBiostatistics & Statistical ProgrammingOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
Linical
Unclaimed · public records
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
Clinical OperationsClinical Data ManagementBiostatistics & Statistical ProgrammingOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
Altasciences
Unclaimed · public records
CRO & CDMO · Phase 1 / Early Clinical Unit, Clinical Operations, Bioanalytical Services
Phase 1 / Early Clinical UnitClinical OperationsBioanalytical ServicesOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
Celerion
Unclaimed · public records
CRO · Phase 1 / Early Clinical Unit, Clinical Operations, Bioanalytical Services
Phase 1 / Early Clinical UnitClinical OperationsBioanalytical ServicesOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
ClinChoice
Unclaimed · public records
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
Clinical OperationsClinical Data ManagementBiostatistics & Statistical ProgrammingOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
Emmes
Unclaimed · public records
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
Clinical OperationsClinical Data ManagementBiostatistics & Statistical ProgrammingOncologyHematologySmall MoleculeMonoclonal Antibody (mAb)
ProPharma
Unclaimed · public records
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
Clinical OperationsClinical Data ManagementBiostatistics & Statistical ProgrammingOncologyCNS / NeurologySmall MoleculeMonoclonal Antibody (mAb)
Novotech
Unclaimed · public records
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
Clinical OperationsClinical Data ManagementBiostatistics & Statistical ProgrammingOncologyHematologySmall MoleculeMonoclonal Antibody (mAb)
Premier Research
Unclaimed · public records
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
Clinical OperationsClinical Data ManagementBiostatistics & Statistical ProgrammingOncologyHematologySmall MoleculeMonoclonal Antibody (mAb)
Veristat
Unclaimed · public records
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
Clinical OperationsClinical Data ManagementBiostatistics & Statistical ProgrammingOncologyHematologySmall MoleculeMonoclonal Antibody (mAb)
Caidya
Unclaimed · public records
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
Clinical OperationsClinical Data ManagementBiostatistics & Statistical ProgrammingOncologyHematologySmall MoleculeMonoclonal Antibody (mAb)
Allucent
Unclaimed · public records
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
Clinical OperationsClinical Data ManagementBiostatistics & Statistical ProgrammingOncologyHematologySmall MoleculeMonoclonal Antibody (mAb)
PSI CRO
Unclaimed · public records
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
Clinical OperationsClinical Data ManagementBiostatistics & Statistical ProgrammingOncologyHematologySmall MoleculeMonoclonal Antibody (mAb)
Worldwide Clinical Trials
Unclaimed · public records
CRO · Clinical Operations, Phase 1 / Early Clinical Unit, Clinical Data Management
Clinical OperationsPhase 1 / Early Clinical UnitClinical Data ManagementOncologyHematologySmall MoleculeMonoclonal Antibody (mAb)
Syneos Health
Unclaimed · public records
CRO · Clinical Operations, Phase 1 / Early Clinical Unit, Clinical Data Management
Clinical OperationsPhase 1 / Early Clinical UnitClinical Data ManagementOncologyHematologySmall MoleculeMonoclonal Antibody (mAb)
Medpace
Unclaimed · public records
CRO · Clinical Operations, Phase 1 / Early Clinical Unit, Clinical Data Management
Clinical OperationsPhase 1 / Early Clinical UnitClinical Data ManagementOncologyHematologySmall MoleculeMonoclonal Antibody (mAb)
Fortrea
Unclaimed · public records
CRO · Clinical Operations, Phase 1 / Early Clinical Unit, Clinical Data Management
Clinical OperationsPhase 1 / Early Clinical UnitClinical Data ManagementOncologyHematologySmall MoleculeMonoclonal Antibody (mAb)
PPD (Thermo Fisher Scientific)
Unclaimed · public records
CRO · Clinical Operations, Phase 1 / Early Clinical Unit, Clinical Data Management
Clinical OperationsPhase 1 / Early Clinical UnitClinical Data ManagementOncologyHematologySmall MoleculeMonoclonal Antibody (mAb)
Parexel
Unclaimed · public records
CRO · Clinical Operations, Phase 1 / Early Clinical Unit, Clinical Data Management
Clinical OperationsPhase 1 / Early Clinical UnitClinical Data ManagementOncologyHematologySmall MoleculeMonoclonal Antibody (mAb)
ICON plc
Unclaimed · public records
CRO · Clinical Operations, Phase 1 / Early Clinical Unit, Clinical Data Management
Clinical OperationsPhase 1 / Early Clinical UnitClinical Data ManagementOncologyHematologySmall MoleculeMonoclonal Antibody (mAb)
IQVIA
Unclaimed · public records
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
Clinical OperationsClinical Data ManagementBiostatistics & Statistical ProgrammingOncologyHematologySmall MoleculeMonoclonal Antibody (mAb)
What kind of CRO work does a CNS / Neurology program need?
CNS and neurology programs carry a problem most other therapeutic areas do not: the brain is walled off. The blood-brain barrier keeps most molecules out, so the first questions a supplier has to answer are whether your compound actually crosses into the central compartment and how much of it reaches the target tissue, not just the plasma. That single fact reshapes the whole outsourcing plan, from the DMPK assays you run to the readouts you trust, and it is why a generalist tox lab that is excellent at oncology can be the wrong partner here.
In discovery and preclinical, the work clusters around brain exposure and the right models. You need DMPK that measures CNS penetration (brain-to-plasma ratios, unbound brain concentration via equilibrium dialysis, P-glycoprotein efflux liability, CSF sampling), efflux and transporter panels, and where relevant a microdialysis study to track free drug in the brain over time. The pharmacology runs in disease-relevant animal models that differ by indication: transgenic and amyloid or tau models for Alzheimer's, MPTP and alpha-synuclein models for Parkinson's, kindling and chemoconvulsant models for epilepsy, EAE for multiple sclerosis, SOD1 and other models for ALS, and a battery of pain and neuropathy assays. Readouts lean on behavioral testing (Morris water maze, rotarod, open field, fear conditioning), electrophysiology (EEG, patch-clamp, MEA), histopathology and neuroinflammation markers, and increasingly imaging such as small-animal PET or MRI. Safety pharmacology has a CNS-specific edge too, since seizure liability and the FOB or Irwin neurobehavioral screen sit right in the core battery.
On the clinical side, CNS trials are operationally hard in ways that show up in the supplier you pick. Endpoints are often subjective rating scales (ADAS-Cog, CDR-SB, UPDRS or MDS-UPDRS, EDSS, MADRS, seizure diaries), so rater training, certification, and central review become real line items, not afterthoughts. Placebo response runs high in CNS, which raises the bar on site selection and monitoring. Biomarkers matter enormously: CSF assays for amyloid, tau and p-tau, neurofilament light chain (NfL) as a neurodegeneration marker, and PET imaging with amyloid, tau, or dopamine-transporter tracers, all of which need a central lab and imaging core that have run these assays before. You will also source clinical operations, biostatistics with experience handling these scales, a central lab, imaging suppliers, pharmacovigilance, and clinical supply, often including formulation work for CNS delivery routes like intrathecal or intranasal administration. On the CDMO side, formulation and delivery for brain penetration (and for biologics, getting a large molecule past the barrier at all) is its own specialist conversation.
How do you choose a CRO for CNS / Neurology?
The deciding factor is genuine therapeutic-area depth, not a logo or the lowest bid. CNS is unforgiving of suppliers learning on your dime, because the models are finicky, the rating scales need trained hands, and a placebo-heavy trial punishes weak site selection. Score two or three candidates against the same written scope and weight the items below over headline price.
- Therapeutic-area experience: ask for completed programs in your specific indication (Alzheimer's, Parkinson's, epilepsy, ALS, MS, migraine, neuropathic pain, depression, schizophrenia), not just "CNS" in general. The right neurodegeneration model is different from the right epilepsy model.
- Relevant disease models and brain-exposure capability: confirm the in vivo model is already validated in-house with historical control data, and that they run CNS-specific DMPK (brain-to-plasma, unbound brain concentration, CSF sampling, P-gp efflux, microdialysis) rather than plasma PK alone.
- Biomarker and imaging access: for clinical work, check they can run or coordinate CSF biomarkers (amyloid, tau, p-tau, NfL) and PET or MRI imaging cores, with validated assays and harmonized reference ranges across sites.
- Rater training and endpoint quality: subjective scales (ADAS-Cog, UPDRS, EDSS, MADRS) live or die on rater certification and central review. Ask how they train, certify, and monitor raters to control variability and placebo response.
- Patient access and site network: CNS enrollment is slow, especially in rare neuromuscular and pediatric neurology indications. Confirm real access to qualified sites, investigators, and patient populations in your geographies, and a credible feasibility track record.
- Regulatory track record and data quality: ask for FDA, EMA, or PMDA inspection history, CDISC-conformant data delivery (SDTM and ADaM), and GLP status for pivotal safety work. Seizure liability and neurobehavioral findings draw reviewer scrutiny, so clean, defensible data matters.
- Capacity and turnaround: a strong lab booked solid can be slower than a good lab with an open slot. Pin down current queue, the named study director or project lead, milestone timelines, and how they handle change orders when a cohort fails or enrollment slips.
Frequently asked questions
Why are CNS and neurology trials considered harder to run than other therapeutic areas?
Three reasons stack up. First, the blood-brain barrier makes drug delivery to the target a problem in its own right, so brain exposure has to be proven, not assumed. Second, many CNS endpoints are subjective rating scales rather than a hard lab value, which introduces rater variability and demands certification and central review. Third, placebo response tends to run high in CNS indications like depression, pain, and Parkinson's, so site selection and monitoring carry more weight. A CRO that has actually run trials in your specific indication is worth paying for here.
What CNS-specific DMPK work should I expect a preclinical CRO to run?
Plasma PK alone is not enough for a CNS program. You want brain-to-plasma ratios, unbound (free) brain concentration measured by equilibrium dialysis, CSF sampling as a surrogate for the central compartment, and P-glycoprotein and BCRP efflux assays to flag whether transporters are pumping your compound back out. For time-resolved free-drug levels in the brain, a microdialysis study is the gold standard. Ask whether the supplier has run these for your modality, since a small-molecule shop may not be set up for a CNS biologic.
Which animal models matter for my CNS indication?
It depends entirely on the disease, which is why indication-specific experience beats general CNS experience. Alzheimer's programs use transgenic amyloid and tau models; Parkinson's uses MPTP and alpha-synuclein models; epilepsy uses kindling and chemoconvulsant (for example pentylenetetrazol or maximal electroshock) models; multiple sclerosis uses EAE; ALS uses SOD1 and related models; and pain programs use a battery of neuropathic and inflammatory assays. Confirm the model is already validated in-house with historical control data rather than being stood up for the first time on your study.
What biomarkers and imaging do CNS clinical trials rely on?
CSF biomarkers are central in neurodegeneration: amyloid-beta, total tau and phosphorylated tau, and neurofilament light chain (NfL) as a marker of axonal damage. Imaging adds amyloid, tau, and dopamine-transporter PET, plus volumetric MRI. These need a central lab and an imaging core that have run the specific assays and tracers before, with validated methods and harmonized reference ranges across sites. Getting the biomarker strategy right early also helps with patient enrichment and can support accelerated-approval discussions.
How do I control placebo response and rater variability in a CNS trial?
It starts with the supplier. Rater training and certification, ideally with central review of scored assessments, reduces variability on scales like ADAS-Cog, UPDRS, MADRS, and EDSS. Careful site and investigator selection, realistic eligibility criteria, and monitoring designed to catch drift all help hold placebo response down. Ask a prospective CRO how they train and certify raters, whether they use central or independent rating, and what their approach is to monitoring scale integrity. These details predict data quality more than the headline bid does.
Can BioBridgeX source CNS suppliers across discovery, preclinical, and clinical in one place?
Yes. A CNS program often pulls in a brain-exposure DMPK lab, an in vivo pharmacology group with the right disease model, a behavioral and electrophysiology specialist, a clinical CRO, a central lab, and an imaging core. You compare qualified CNS suppliers and contract directly with the ones you choose, in one place, with BioBridgeX acting as the neutral marketplace and not a party to the agreement. It is free for buyers, suppliers pay a flat 2 percent fee, and coverage spans every indication and modality, so the same account carries forward as your program advances.
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