Outsourcing a peptide program means matching a CRO or CDMO to solid-phase or solution-phase synthesis, purification, and the analytical work that proves identity and purity. It spans discovery synthesis through GMP drug substance, fill-finish, and stability. On BioBridgeX, buyers source and compare qualified peptide suppliers, free for buyers, and contract directly with the supplier they choose.
Peptide CRO and CDMO vendors (126)
UNIQ Trials
Apeloa Pharmaceutical
TRiCBIO
VCHP Clinical Solutions
Famar Group
CDMO · Formulation Development, LNP / Delivery Formulation, Process Development
AbbVie Contract Manufacturing
CRO & CDMO · Drug Substance: Small Molecule / API, Drug Substance: Biologics, Formulation Development
Singota Solutions
CDMO · Aseptic Fill-Finish, Drug Product Manufacturing, QC & Release Testing
Novocol Pharma
CDMO · Formulation Development, LNP / Delivery Formulation, Process Development
Lifecore Biomedical
CDMO · Formulation Development, LNP / Delivery Formulation, Process Development
Kindeva Drug Delivery
CDMO · Formulation Development, LNP / Delivery Formulation, Process Development
Grand River Aseptic Manufacturing (GRAM)
CDMO · Formulation Development, LNP / Delivery Formulation, Process Development
Curia Global
CRO & CDMO · Drug Substance: Small Molecule / API, Drug Substance: Biologics, Formulation Development
Jubilant HollisterStier
CDMO · Formulation Development, LNP / Delivery Formulation, Process Development
Siegfried Holding
CRO & CDMO · Drug Substance: Small Molecule / API, Formulation Development, LNP / Delivery Formulation
Aenova Group
CDMO · Formulation Development, LNP / Delivery Formulation, Process Development
Fresenius Kabi Contract Manufacturing
CDMO · Formulation Development, LNP / Delivery Formulation, Process Development
Simtra BioPharma Solutions
CDMO · Formulation Development, LNP / Delivery Formulation, Process Development
Vetter Pharma
CDMO · Formulation Development, LNP / Delivery Formulation, Process Development
PCI Pharma Services
CDMO · Aseptic Fill-Finish, Drug Product Manufacturing, Formulation Development
GeneQuantum Healthcare
CDMO · ADC / Bioconjugation, Medicinal & Synthetic Chemistry, Process Development
AsymBio (Asymchem)
CDMO · ADC / Bioconjugation, Drug Substance: Biologics, Drug Substance: Small Molecule / API
BSP Pharmaceuticals
CDMO · ADC / Bioconjugation, Aseptic Fill-Finish, Drug Product Manufacturing
Ajinomoto Bio-Pharma Services (Aji Bio-Pharma)
CDMO · ADC / Bioconjugation, Drug Substance: Biologics, Peptide / Oligo Synthesis
WuXi XDC
CDMO · ADC / Bioconjugation, Drug Substance: Biologics, Drug Substance: Small Molecule / API
WuXi STA (STA Pharmaceutical)
CDMO · Peptide / Oligo Synthesis, Drug Substance: Small Molecule / API, ADC / Bioconjugation
CPC Scientific
CDMO · Peptide / Oligo Synthesis, Process Development, Analytical Development
Senn Chemicals (Granules India)
CDMO · Peptide / Oligo Synthesis, Process Development, Analytical Development
Recipharm
CDMO · mRNA / RNA Manufacturing, LNP / Delivery Formulation, Drug Product Manufacturing
Evonik (Health Care)
CDMO · LNP / Delivery Formulation, Formulation Development, Drug Product Manufacturing
Ajinomoto Bio-Pharma Services
CRO & CDMO · Peptide / Oligo Synthesis, ADC / Bioconjugation, Drug Substance: Small Molecule / API
CSBio
CDMO · Peptide / Oligo Synthesis, Process Development, Analytical Development
Bio-Synthesis Inc
CDMO · Peptide / Oligo Synthesis, mRNA / RNA Manufacturing, ADC / Bioconjugation
WuXi TIDES (WuXi AppTec)
CRO & CDMO · Peptide / Oligo Synthesis, ADC / Bioconjugation, Medicinal & Synthetic Chemistry
Kaneka Eurogentec
CDMO · Peptide / Oligo Synthesis, Plasmid DNA Manufacturing, Drug Substance: Biologics
PolyPeptide Group
CDMO · Peptide / Oligo Synthesis, Process Development, Analytical Development
Richter BioLogics (Richter-Helm)
CDMO · Process Development, Analytical Development, Drug Substance: Biologics
Cytovance Biologics
CDMO · Cell Line / Strain Development, Process Development, Analytical Development
BioVectra
CDMO · Process Development, Analytical Development, Drug Substance: Biologics
Boehringer Ingelheim BioXcellence
CDMO · Cell Line / Strain Development, Process Development, Analytical Development
Teva API (TAPI)
CDMO · Drug Substance: Small Molecule / API, Process Development, Analytical Development
Bachem
CDMO · Peptide / Oligo Synthesis, Process Development, Analytical Development
Veranova
CDMO · Medicinal & Synthetic Chemistry, Process Development, Drug Substance: Small Molecule / API
Pfizer CentreOne
CRO & CDMO · Drug Substance: Small Molecule / API, Process Development, Analytical Development
Thermo Fisher Scientific (Patheon)
CRO & CDMO · Process Development, Drug Substance: Small Molecule / API, Analytical Development
Divi's Laboratories
CDMO · Medicinal & Synthetic Chemistry, Process Development, Drug Substance: Small Molecule / API
Dr. Reddy's Custom Pharma Services (CPS)
CRO & CDMO · Process Development, Drug Substance: Small Molecule / API, Analytical Development
EUROAPI
CDMO · Drug Substance: Small Molecule / API, Process Development, Analytical Development
Olon Group
CDMO · Drug Substance: Small Molecule / API, Process Development, Analytical Development
Fareva
CRO & CDMO · Drug Substance: Small Molecule / API, Process Development, Analytical Development
CordenPharma
CRO & CDMO · Drug Substance: Small Molecule / API, Process Development, Analytical Development
WuXi STA (WuXi AppTec)
CRO & CDMO · Medicinal & Synthetic Chemistry, Process Development, Analytical Development
Asymchem
CRO & CDMO · Medicinal & Synthetic Chemistry, Process Development, Drug Substance: Small Molecule / API
Cambrex
CDMO · Drug Substance: Small Molecule / API, Process Development, Analytical Development
Lonza
CRO & CDMO · Drug Substance: Small Molecule / API, Process Development, Analytical Development
Eurofins (Pharma Discovery & Bioanalytical Services)
CRO & CDMO · Bioanalytical Services, Central Laboratory Services, Genetic Toxicology
QPS Holdings
CRO · Bioanalytical Services, DMPK / ADME, GLP Toxicology
Sannova Analytical
CRO · Bioanalytical Services, Immunogenicity & Immunotoxicology, Biomarker Discovery & Development
NorthEast BioLab
CRO · Bioanalytical Services, Immunogenicity & Immunotoxicology, Biomarker Discovery & Development
Nucro-Technics
CRO & CDMO · GLP Toxicology, Genetic Toxicology, Bioanalytical Services
Gentronix
CRO · Genetic Toxicology, In Vitro / Early Toxicology
Synexa Life Sciences
CRO · Biomarker Discovery & Development, Bioanalytical Services, Immunogenicity & Immunotoxicology
Simulations Plus
CRO · PK/PD & Modeling, DMPK / ADME, In Vitro / Early Toxicology
Certara
CRO · PK/PD & Modeling, Biostatistics & Statistical Programming, Medical Writing
Labcorp
CRO & CDMO · Central Laboratory Services, GLP Toxicology, Safety Pharmacology
BioAgilytix Labs
CRO · Bioanalytical Services, Immunogenicity & Immunotoxicology, Biomarker Discovery & Development
Pharmacology Discovery Services (PDS)
CRO · In Vitro Pharmacology, Safety Pharmacology, Assay Development & Screening
Cresset
CRO · Hit-to-Lead, Lead Optimization, Medicinal & Synthetic Chemistry
Schrodinger
CRO · Target ID & Validation, Hit-to-Lead, Lead Optimization
ChemDiv
CRO · Assay Development & Screening, Hit-to-Lead, Lead Optimization
Enamine
CRO · Assay Development & Screening, Hit-to-Lead, Lead Optimization
GenScript
CRO & CDMO · Assay Development & Screening, Protein Sciences & Reagents, Medicinal & Synthetic Chemistry
HitGen
CRO · Assay Development & Screening, Hit-to-Lead, Lead Optimization
X-Chem
CRO · Assay Development & Screening, Hit-to-Lead, Lead Optimization
BioDuro
CRO & CDMO · Target ID & Validation, Assay Development & Screening, Hit-to-Lead
Aurigene Pharmaceutical Services
CRO & CDMO · Target ID & Validation, Assay Development & Screening, Hit-to-Lead
Selvita
CRO · Target ID & Validation, Assay Development & Screening, Hit-to-Lead
Sygnature Discovery
CRO · Target ID & Validation, Assay Development & Screening, Hit-to-Lead
Syngene International
CRO & CDMO · GLP Toxicology, Safety Pharmacology, DMPK / ADME
Aragen Life Sciences
CRO & CDMO · DMPK / ADME, GLP Toxicology, Safety Pharmacology
Sai Life Sciences
CRO & CDMO · DMPK / ADME, In Vitro / Early Toxicology, GLP Toxicology
JOINN Laboratories / Biomere
CRO · GLP Toxicology, Safety Pharmacology, Toxicokinetics (TK)
KCAS Bio
CRO · Bioanalytical Services, Biomarker Discovery & Development, Immunogenicity & Immunotoxicology
Lovelace Biomedical
CRO · GLP Toxicology, Safety Pharmacology, Toxicokinetics (TK)
Vivotecnia
CRO · GLP Toxicology, Safety Pharmacology, Genetic Toxicology
Nuvisan
CRO & CDMO · DMPK / ADME, Bioanalytical Services, In Vitro / Early Toxicology
Oncodesign Services
CRO · In Vitro Pharmacology, DMPK / ADME, Bioanalytical Services
Biotrial
CRO · Safety Pharmacology, GLP Toxicology, Toxicokinetics (TK)
BioAgilytix
CRO · Bioanalytical Services, Immunogenicity & Immunotoxicology, Biomarker Discovery & Development
Gentronix (a Scantox company)
CRO · Genetic Toxicology, In Vitro / Early Toxicology, Assay Development & Screening
Scantox
CRO · GLP Toxicology, Safety Pharmacology, Genetic Toxicology
Cyprotex (an Evotec company)
CRO · In Vitro / Early Toxicology, DMPK / ADME, Genetic Toxicology
Evotec
CRO & CDMO · In Vitro / Early Toxicology, DMPK / ADME, Safety Pharmacology
Frontage Laboratories
CRO & CDMO · GLP Toxicology, Safety Pharmacology, Toxicokinetics (TK)
Eurofins Discovery
CRO · In Vitro / Early Toxicology, Safety Pharmacology, DMPK / ADME
WuXi AppTec
CRO & CDMO · GLP Toxicology, Safety Pharmacology, Genetic Toxicology
Inotiv
CRO · GLP Toxicology, Safety Pharmacology, Genetic Toxicology
Labcorp (Labcorp Drug Development / former Covance)
CRO & CDMO · GLP Toxicology, Safety Pharmacology, Genetic Toxicology
Charles River Laboratories
CRO & CDMO · GLP Toxicology, Safety Pharmacology, Genetic Toxicology
Avance Clinical
CRO · Clinical Operations, Phase 1 / Early Clinical Unit, Clinical Data Management
Cromos Pharma
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
George Clinical (Emerald Clinical)
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
TFS HealthScience
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
Pharmaron
CRO & CDMO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
WuXi Clinical
CRO · Clinical Operations, Phase 1 / Early Clinical Unit, Clinical Data Management
Tigermed
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
CMIC Group
CRO & CDMO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
Linical
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
Altasciences
CRO & CDMO · Phase 1 / Early Clinical Unit, Clinical Operations, Bioanalytical Services
Celerion
CRO · Phase 1 / Early Clinical Unit, Clinical Operations, Bioanalytical Services
ClinChoice
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
ProPharma
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
Novotech
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
Premier Research
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
Veristat
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
Caidya
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
Allucent
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
PSI CRO
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
Worldwide Clinical Trials
CRO · Clinical Operations, Phase 1 / Early Clinical Unit, Clinical Data Management
Syneos Health
CRO · Clinical Operations, Phase 1 / Early Clinical Unit, Clinical Data Management
Medpace
CRO · Clinical Operations, Phase 1 / Early Clinical Unit, Clinical Data Management
Fortrea
CRO · Clinical Operations, Phase 1 / Early Clinical Unit, Clinical Data Management
PPD (Thermo Fisher Scientific)
CRO · Clinical Operations, Phase 1 / Early Clinical Unit, Clinical Data Management
Parexel
CRO · Clinical Operations, Phase 1 / Early Clinical Unit, Clinical Data Management
ICON plc
CRO · Clinical Operations, Phase 1 / Early Clinical Unit, Clinical Data Management
IQVIA
CRO · Clinical Operations, Clinical Data Management, Biostatistics & Statistical Programming
What does it take to develop and manufacture a peptide drug?
Peptides sit in an awkward middle ground between small molecules and biologics, and that is exactly why supplier fit matters so much. A peptide is built one amino acid at a time, usually by solid-phase peptide synthesis (SPPS), and every coupling step is a chance to introduce a deletion sequence, a racemized residue, or an aggregation problem you will spend weeks chasing later. The chemistry that makes a clean 12-mer is not the chemistry that makes a 40-residue therapeutic with three disulfide bridges, a lipid conjugate, or a head-to-tail cyclization. So the first thing to settle with any provider is whether they have actually made molecules like yours, at the length and complexity you need, not whether they run a peptide synthesizer.
Early on, the work is discovery and optimization: sequence design, analog synthesis, stability and protease-resistance screening, and the modifications that turn a fragile native peptide into a drug (N-methylation, unnatural amino acids, PEGylation or lipidation for half-life, cyclization for rigidity and target selectivity). This is largely non-GLP, decision-grade chemistry, and a discovery-focused peptide CRO lives here. As you move toward the clinic, the center of gravity shifts to CMC and manufacturing: a defined synthesis route, validated purification (almost always preparative reverse-phase HPLC), and an analytical package that nails down identity, purity, counterion and water content, and the impurity profile. Mass spec, analytical HPLC, amino acid analysis, and chiral or peptide-mapping methods all earn their place here.
This is where specialist peptide CDMOs pull away from generalist chemical manufacturers. A shop that is excellent at small-molecule API may underestimate how much a peptide program lives or dies on purification capacity and on controlling closely related impurities (single-residue deletions, oxidation, diastereomers) that a routine HPLC method will not even separate. Specialists bring large-scale SPPS or hybrid solution-phase routes, the prep-HPLC and lyophilization throughput to actually make kilograms, and analysts who have characterized these impurity classes before. Longer or more modified peptides push you firmly toward a specialist; a short, simple linear peptide gives you more room to use a capable generalist.
How do you choose a CRO or CDMO for peptide work?
Start with fit to your specific molecule, not the size of the logo or the headline price. Score two or three suppliers against the same written scope (the sequence, the length, the modifications, the scale, and the purity spec you need) so the quotes measure the same work rather than three differently shaped guesses. The cheapest quote on a complex peptide is rarely the cheapest outcome, because a failed batch or an impurity you cannot clear forces a repeat that costs you months. Work the checklist below.
- Relevant platform and track record: confirm they routinely make peptides of your length and type (linear, cyclic, stapled, disulfide-rich, conjugated or lipidated) and ask to see comparable structures they have produced, not a generic capabilities slide. SPPS depth, plus solution-phase or hybrid routes for longer sequences and larger scale, is the real differentiator.
- GxP status and analytical capability for this modality: match the quality system to your stage. Research analogs run non-GLP; IND-enabling and clinical material need GMP drug substance with full release testing. Confirm the analytical toolkit handles peptides specifically: prep and analytical RP-HPLC, LC-MS and high-res mass spec, amino acid analysis, peptide mapping, counterion and water (Karl Fischer) content, and methods that resolve deletion sequences and diastereomers, not just a single purity number.
- Capacity and scale: ask how much they can actually make at your stage and whether they can carry you from grams to kilograms without a technology transfer to a different site. Purification throughput (prep-HPLC columns and loading) and lyophilization capacity are the usual bottlenecks, so probe those, not just synthesizer count. Check current queue and realistic lead time, since a strong lab booked solid can be slower than a good lab with an open slot.
- Regulatory experience: for clinical material, confirm they have supported INDs or equivalent filings with peptide drug substance, can supply the CMC sections and method validation a regulator will scrutinize, and understand the impurity qualification and specification-setting that peptides demand. Stability program design and ICH-aligned storage data matter once you are in the clinic.
- IP and confidentiality: get a CDA in place before you disclose your sequence, since the sequence itself is the asset. Settle ownership of process know-how, any supplier-developed synthesis or purification improvements, and the analytical methods, in writing before work starts.
Frequently asked questions
Do I need a specialist peptide CDMO, or can a generalist chemical manufacturer handle it?
What is the difference between solid-phase and solution-phase peptide synthesis, and why does it matter?
What analytical testing should a peptide drug substance go through?
When does a peptide program need GMP manufacturing?
How do I keep my peptide sequence confidential when I send it to a supplier?
How does sourcing peptide suppliers on BioBridgeX work, and what does it cost buyers?
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